Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 19/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966124 | 0.87 | ESR1 (0.53) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL8966131 | 0.82 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL8965856 | 0.72 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL8966114 | 0.72 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL18150401 | 0.71 | ESR1 (0.75) | ESR1ESR2 | |
| SCHEMBL9741976 | 0.71 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL9571852 | 0.69 | ESR1 (0.54) | ESR1ESR2ALDH1A1 | |
| SCHEMBL8966236 | 0.69 | ESR1 (0.53) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL7525411 | 0.68 | ESR1 (0.85) | ESR1ESR2 | |
| SCHEMBL8966205 | 0.68 | ESR1 (1.00) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524742-B1 | Benzo(a)fluorene compounds | LILLY CO ELI (US) | 1996-02-28 | — | — | EP | disclosed |