Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8966687 | 0.99 | ALDH1A1 (0.41) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 | |
| SCHEMBL8967342 | 0.86 | HDAC1 (0.44) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 | |
| SCHEMBL8616106 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL8966843 | 0.85 | L3MBTL1 (0.46) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 | |
| SCHEMBL8966793 | 0.85 | HDAC1 (0.37) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL8617887 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL8966715 | 0.84 | L3MBTL1 (0.38) | ALDH1A1SMN1; SMN2HDAC1MAPTLIN28A | |
| SCHEMBL8966322 | 0.84 | CYP2C9 (0.46) | ALDH1A1CYP1A2TSHRMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8967045 | 0.83 | CYP2C9 (0.44) | ALDH1A1CYP1A2TSHRMAPTMEN1 | |
| SCHEMBL2189143 | 0.78 | TRPM8 (0.47) | ALDH1A1CYP1A2TSHRSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561147-A | ANTIINFLAMMATORY AGENT, ANTIPYRETIC, ANALGESICS, ANTIALLERGENS, IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| US-5457106-A | Antiinflammatory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| US-5389658-A | Administering as antipyretic, antiinflammatory, analgesic, antiallergic, or immunosupressive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0612729-A2 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5246948-A | Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0522606-A2 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |