Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | BAX | Q07812 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715309 | 0.89 | MAPT (0.54) | LTA4HMEN1KMT2ATSHRNAAA | |
| SCHEMBL9503707 | 0.88 | MAPK1 (0.53) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL9381581 | 0.86 | TSHR (0.64) | TSHRARALDH1A1HSP90AA1 | |
| SCHEMBL29349910 | 0.85 | MAOA (0.52) | MEN1KMT2ANAAAARMITF | |
| SCHEMBL3716891 | 0.85 | MAOA (0.52) | MEN1KMT2ANAAAARMITF | |
| SCHEMBL3167834 | 0.85 | LTA4H (0.73) | LTA4HNR1H2BAXMEN1KMT2A | |
| SCHEMBL249608 | 0.85 | LTA4H (0.73) | LTA4HNR1H2BAXMEN1KMT2A | |
| SCHEMBL29924283 | 0.85 | RHEB (0.52) | MEN1KMT2ATSHRARMAPK1 | |
| SCHEMBL6206121 | 0.85 | RHEB (0.52) | MEN1KMT2ATSHRARMAPK1 | |
| SCHEMBL3790523 | 0.83 | LTA4H (0.57) | LTA4HMEN1KMT2ATSHRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404720-B1 | Pesticidal agent | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | claimed |
| EP-0404720-A2 | Pesticidal agent | CIBA-GEIGY AG (CH) | 1990-12-27 | — | — | EP | claimed |
| JP-3031249-A | — | — | None | — | — | JP | disclosed |
| EP-0404720-B1 | Pesticidal agent | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| EP-0394191-B1 | Sulfenylated carbamic acid esters | CIBA GEIGY AG (CH) | 1994-02-02 | — | — | EP | disclosed |
| US-5192803-A | Insecticides, miticides, larvicides, ovicides | CIBA-GEIGY CORPORATION (US) | 1993-03-09 | — | — | US | disclosed |
| US-5166153-A | Insecticides or miticides | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5141956-A | Agricultural insecticides | CIBA-GEIGY CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |
| JP-H0331249-A | PESTICIDAL COMPOSITION | CIBA GEIGY AG | 1991-02-12 | — | — | JP | disclosed |
| EP-0404720-A2 | Pesticidal agent | CIBA-GEIGY AG (CH) | 1990-12-27 | — | — | EP | disclosed |
| EP-0395582-A2 | Bisacylethylamines | CIBA-GEIGY AG (CH) | 1990-10-31 | — | — | EP | disclosed |
| EP-0394191-A1 | Sulfenylated carbamic acid esters | CIBA-GEIGY AG (CH) | 1990-10-24 | — | — | EP | disclosed |
| US-4625048-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0072475-B1 | CARBAMIC ESTERS, PREPARATION THEREOF, PESTICIDAL COMPOSITIONS ON THE BASIS OF THESE COMPOUNDS AND THEIR USE IN COMBATING PESTS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-08-20 | — | — | EP | disclosed |
| US-4607051-A | Carbamic acid compound and use as a pesticide | HOFFMANN-LA ROCHE INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4413010-A | Carbamic acid esters and use as pesticides | HOFFMANN-LA ROCHE INC. (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0072475-A2 | Carbamic esters, preparation thereof, pesticidal compositions on the basis of these compounds and their use in combating pests | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-02-23 | — | — | EP | disclosed |