SCHEMBL9503707

SCHEMBL9503707

O=C(c1ccc(O)cc1)c1ccc(Oc2cccc(Cl)c2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.53
NAAA Q02083 1/20 0.52
SRD5A2 P31213 1/20 0.51
PARP10 Q53GL7 2/20 0.49
RXRA P19793 1/20 0.48
RXRB P28702 1/20 0.48
RXRG P48443 1/20 0.48
STS P08842 1/20 0.48
POLB P06746 1/20 0.48
TNKS O95271 1/20 0.47
PARP15 Q460N3 1/20 0.47
PARP14 Q460N5 1/20 0.47
TNKS2 Q9H2K2 1/20 0.47
PARP2 Q9UGN5 1/20 0.47
LTA4H P09960 1/20 0.47
NR1H2 P55055 1/20 0.47
BAX Q07812 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8966889 0.88 LTA4H (0.59) MAPK1NAAALTA4HNR1H2BAX
SCHEMBL6860158 0.86 TNKS (0.57) NAAASRD5A2PARP10STSPOLB
SCHEMBL14191212 0.83 SRD5A2 (0.58) MAPK1SRD5A2PARP10POLBTNKS
SCHEMBL13250810 0.83 SRD5A2 (0.58) MAPK1SRD5A2PARP10POLBTNKS
SCHEMBL14191218 0.83 SRD5A2 (0.58) MAPK1SRD5A2PARP10POLBTNKS
SCHEMBL3677325 0.83 SRD5A2 (0.53) NAAASRD5A2PARP10RXRARXRB
SCHEMBL8967203 0.83 MAPK1 (0.77) MAPK1SRD5A2PARP10ESR1ESR2
SCHEMBL9506642 0.83 MAPK1 (0.77) MAPK1SRD5A2PARP10ESR1ESR2
SCHEMBL9507303 0.83 MAPK1 (0.77) MAPK1SRD5A2PARP10ESR1ESR2
SCHEMBL6521756 0.83 SRD5A2 (0.62) SRD5A2PARP10STSPOLBTNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0344688-B1 PROCESS FOR PRODUCING A PHENOLATE AND PROCESS FOR PRODUCING AN AROMATIC POLYETHER KETONE EMPLOYING IT MITSUBISHI KASEI CORPORATION (JP) 1993-08-04 EP disclosed
US-5171821-A Azeotropically distilling off water with an organic solvent to obtain the phenolate formed from an alkali compound and a chlorophenylene hydroxyphenylene ketone MITSUBISHI KASEI CORPORATION (JP) 1992-12-15 US disclosed
EP-0344688-A2 Process for producing a phenolate and process for producing an aromatic polyether ketone employing it MITSUBISHI KASEI CORPORATION (JP) 1989-12-06 EP disclosed