SCHEMBL8966918

SCHEMBL8966918

CC(C)(C)c1c(O)ccc(-c2ccc(O)cc2)c1C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
TYR P14679 2/20 0.43
HSD17B10 Q99714 3/20 0.42
NR1I2 O75469 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2C9 P11712 1/20 0.42
MIF P14174 1/20 0.42
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.42
NFE2L2 Q16236 1/20 0.42
ESR1 P03372 7/20 0.40
ESR2 Q92731 4/20 0.40
ALOX5 P09917 2/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP3A4 P08684 1/20 0.38
AR P10275 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL28076397 0.87 LMNA (0.55) LMNATYRHSD17B10NR1I2ALDH1A1
SCHEMBL30105383 0.83 BACE1 (0.48) LMNAHSD17B10ALDH1A1ALOX15HTT
SCHEMBL28008088 0.83 BACE1 (0.48) LMNAHSD17B10ALDH1A1ALOX15HTT
SCHEMBL5694506 0.82 ALDH1A1 (0.42) LMNATYRHSD17B10NR1I2ALDH1A1
SCHEMBL70068 0.79 ALDH1A1 (0.48) LMNATYRHSD17B10NR1I2ALDH1A1
SCHEMBL30027143 0.79 ALDH1A1 (0.48) LMNATYRHSD17B10NR1I2ALDH1A1
SCHEMBL27963029 0.79 ALDH1A1 (0.48) LMNATYRHSD17B10NR1I2ALDH1A1
SCHEMBL29485632 0.78 KIF11 (0.47) HSD17B10ESR1ESR2ALOX5CA12
SCHEMBL3980314 0.77 MGAM (0.35) LMNATYRHSD17B10NR1I2ALDH1A1
SCHEMBL30708513 0.75 KIF11 (0.39) HSD17B10ESR1ESR2ALOX5CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693962-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1996-01-31 EP claimed
WO-1994023830-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'Air Liquide Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 1994-10-27 WO claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
CN-111171545-B Polycarbonate resin composition, method for producing same, and molded article 三菱化学株式会社 2023-04-28 CN disclosed
CN-114364654-A Method for producing aromatic diether compound 本州化学工业株式会社 2022-04-15 CN disclosed
WO-2020218134-A1 METHOD FOR PRODUCING TETRACARBOXYLIC ACID DIANHYDRIDE 本州化学工業株式会社 2020-10-29 WO disclosed