Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210749 | 0.87 | MAPT (0.60) | CDC25BMAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL8967035 | 0.83 | CDC25B (0.56) | CDC25BMAPTTDP1HPGDKDM4E | |
| SCHEMBL4103770 | 0.82 | CDC25B (0.68) | CDC25BMAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL29360359 | 0.80 | MAPT (0.59) | MAPTTDP1HPGDKDM4EALDH1A1 | |
| SCHEMBL5458 | 0.80 | MAPT (0.59) | MAPTTDP1HPGDKDM4EALDH1A1 | |
| SCHEMBL11963917 | 0.80 | LDHA (0.44) | CDC25BMAPTTDP1HPGDKDM4E | |
| SCHEMBL24895097 | 0.80 | CDC25B (0.56) | CDC25BMAPTTDP1HPGDKDM4E | |
| SCHEMBL8461417 | 0.80 | CDC25B (0.52) | CDC25BMAPTTDP1HPGDKDM4E | |
| SCHEMBL8460917 | 0.80 | CDC25B (0.52) | CDC25BMAPTTDP1HPGDKDM4E | |
| SCHEMBL23277173 | 0.79 | MAPT (0.58) | MAPTTDP1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498628-A | ANTIPSYCHOTIC, PSYCHOSTIMULATORY, ANTIAUTISTIC, ANTIDEPRESSANT AND HYPOTENSIVE AGENTS, PARKINSON'S DISEASE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-03-12 | — | — | US | disclosed |
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0394451-A1 | MUFFLER | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |
| EP-0236837-A2 | Mixtures of polycarbonate polysiloxane block cocondensates and thermotropic polymers, process for preparing them and their use in making mouldings, filaments, fibres and foils | BAYER AG (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0232777-A2 | Method of manufacturing parts of thermotropic liquid crystalline plastics with a defined orientation of the liquid crystal polymer molecule, and the parts so produced | BAYER AG (DE) | 1987-08-19 | — | — | EP | disclosed |