Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504326 | 0.86 | CDC25B (0.50) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9679999 | 0.86 | TDP1 (0.55) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8966935 | 0.83 | CDC25B (0.56) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4103770 | 0.82 | CDC25B (0.68) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL976330 | 0.81 | KDM4E (0.57) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8967454 | 0.81 | LMNA (0.46) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL152563 | 0.80 | MAPT (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29603325 | 0.80 | MAPT (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8460917 | 0.80 | CDC25B (0.52) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8461417 | 0.80 | CDC25B (0.52) | CDC25BALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |