Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967031 | 0.86 | SLC18A3 (0.63) | DRD2SLC18A3SIGMAR1 | |
| SCHEMBL6998658 | 0.83 | DRD2 (0.59) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8001944 | 0.82 | DRD2 (0.65) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8011291 | 0.82 | DRD2 (0.65) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9967718 | 0.82 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8001978 | 0.81 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL11790517 | 0.80 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8012789 | 0.79 | DRD2 (0.60) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8017474 | 0.78 | SLC18A3 (0.63) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8571166 | 0.77 | DRD2 (0.59) | DRD2HTR1AHTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |