Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966946 | 0.86 | DRD2 (0.52) | SLC18A3SIGMAR1DRD2 | |
| SCHEMBL7238271 | 0.82 | SLC18A3 (0.81) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL9967730 | 0.81 | DRD2 (0.64) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL6591133 | 0.80 | SLC18A3 (0.78) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL7259165 | 0.80 | SIGMAR1 (0.75) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7388033 | 0.79 | SLC18A3 (0.76) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL29110823 | 0.79 | SLC18A3 (0.66) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7281715 | 0.78 | SLC18A3 (1.00) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL2554214 | 0.75 | SIGMAR1 (0.69) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL3458641 | 0.75 | SIGMAR1 (0.69) | SLC18A3SIGMAR1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |