Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681878 | 1.00 | SRD5A2 (0.70) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL51827 | 0.92 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL10697158 | 0.92 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL1681512 | 0.92 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL9065412 | 0.92 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL9248915 | 0.91 | MAPK1 (0.87) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL10953514 | 0.91 | RAB9A (0.67) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL9777922 | 0.91 | MAPK1 (0.87) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL2168586 | 0.91 | MAPK1 (0.87) | SRD5A2MAPK1HPGDCES2CES1 | |
| SCHEMBL10874927 | 0.91 | SRD5A2 (0.65) | SRD5A2MAPK1HPGDCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109943543-B | Alcohol dehydrogenase mutant and preparation method and application thereof | 上海健康医学院 | 2020-12-11 | — | — | CN | claimed |
| EP-0306051-B1 | Process for production of aromatic polyethers | MITSUBISHI GAS CHEMICAL CO (JP) | 1996-03-06 | — | — | EP | claimed |
| CN-109943543-B | Alcohol dehydrogenase mutant and preparation method and application thereof | 上海健康医学院 | 2020-12-11 | — | — | CN | disclosed |
| WO-2019153633-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153634-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHESIS OF BIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153632-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| CN-109943543-A | Alcohol dehydrogenase mutant and its preparation method and application | 上海健康医学院 | 2019-06-28 | — | — | CN | disclosed |
| US-4760127-A | Reacting dihalogen aromatics and alkali metal sulfide in presence of a monohalogen compound and a monomercapto compound | BAYER AG (DE) | 1988-07-26 | — | — | US | disclosed |