Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967832 | 0.95 | KEAP1 (0.51) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL8967255 | 0.95 | KEAP1 (0.54) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL31548342 | 0.88 | KEAP1 (0.50) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL712251 | 0.86 | KDM4E (0.61) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL30918587 | 0.84 | POLB (0.54) | KMT2AKDM4EMAPTPOLBMEN1 | |
| SCHEMBL8072637 | 0.84 | POLB (0.54) | KMT2AKDM4EMAPTPOLBMEN1 | |
| SCHEMBL1554060 | 0.84 | KMT2A (0.59) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL2426327 | 0.83 | KEAP1 (0.66) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL27194490 | 0.83 | KDM4E (0.45) | KEAP1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL30507896 | 0.82 | KEAP1 (0.59) | KEAP1KMT2AKDM4EGFERRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571579-A | FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM | HITACHI CHEMICAL COMPANY, LTD (JP) | 1996-11-05 | — | — | US | disclosed |