SCHEMBL30918587

SCHEMBL30918587

O=C(O)c1ccc(Oc2c(F)c(F)c(Oc3ccc(C(=O)O)c(C(=O)O)c3)c(F)c2F)cc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.54
ALDH1A1 P00352 1/20 0.53
HPSE Q9Y251 1/20 0.47
HTT P42858 2/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.44
PYGL P06737 7/20 0.43
PYGM P11217 7/20 0.43
APEX1 P27695 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 3/20 0.43
LMNA P02545 2/20 0.43
GALK1 P51570 1/20 0.42
CASP6 P55212 1/20 0.42
MCL1 Q07820 1/20 0.42
PLEC Q15149 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 2/20 0.41
HSP90AA1 P07900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072637 1.00 POLB (0.54) POLBALDH1A1HPSEHTTHPGD
SCHEMBL6567615 0.95 POLB (0.50) POLBALDH1A1HPSEHTTHPGD
SCHEMBL8967249 0.84 KEAP1 (0.56) POLBALDH1A1HTTHPGDHSD17B10
SCHEMBL24407683 0.84 ALDH1A1 (0.52) ALDH1A1HTTHPGDHSD17B10LMNA
SCHEMBL29364655 0.84 POLB (0.70) POLBALDH1A1HPSEHSD17B10PYGL
SCHEMBL49365 0.84 POLB (0.70) POLBALDH1A1HPSEHSD17B10PYGL
SCHEMBL29426403 0.84 POLB (0.70) POLBALDH1A1HPSEHSD17B10PYGL
SCHEMBL6318642 0.83 POLB (0.56) POLBALDH1A1HPSEHSD17B10PYGL
SCHEMBL31118332 0.83 ALDH1A1 (0.49) POLBALDH1A1HTTHPGDHSD17B10
SCHEMBL145176 0.82 POLB (0.73) POLBALDH1A1HPSEHSD17B10PYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500811-B Polyimide adhesive, and preparation method and application thereof 南北兄弟药业投资有限公司 2025-04-18 CN disclosed
CN-117736472-A Preparation method of color-adjustable fluorine polyimide film 厦门大学 2024-03-22 CN disclosed