Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL8966538 | 0.94 | DRD3 (0.45) | SIGMAR1DRD3 | |
| Maleic Acid SCHEMBL8968082 | 0.94 | DRD3 (0.45) | SIGMAR1DRD3 | |
| SCHEMBL8967226 | 0.85 | SIGMAR1 (0.66) | SIGMAR1DRD3 | |
| SCHEMBL8967338 | 0.85 | DRD3 (0.59) | SIGMAR1DRD3 | |
| Hydrochloric Acid SCHEMBL9223939 | 0.85 | SIGMAR1 (0.52) | SIGMAR1DRD3 | |
| SCHEMBL8966528 | 0.85 | SIGMAR1 (0.50) | SIGMAR1DRD3 | |
| Hydrochloric Acid SCHEMBL9229456 | 0.85 | SIGMAR1 (0.52) | SIGMAR1DRD3 | |
| SCHEMBL8967329 | 0.85 | SIGMAR1 (0.50) | SIGMAR1DRD3 | |
| Hydrochloric Acid SCHEMBL8967140 | 0.84 | SIGMAR1 (0.49) | SIGMAR1DRD3 | |
| Hydrochloric Acid SCHEMBL8966597 | 0.84 | DRD3 (0.58) | SIGMAR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |