SCHEMBL8967726

SCHEMBL8967726

O=C(c1ccc(Cl)cc1)c1ccc2cc(Cl)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.57
MAPK1 P28482 1/20 0.57
HPGD P15428 1/20 0.55
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
CNR2 P34972 2/20 0.49
CNR1 P21554 1/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
HSD17B14 Q9BPX1 1/20 0.47
ELANE P08246 1/20 0.47
CLK1 P49759 1/20 0.47
DYRK1A Q13627 1/20 0.47
DYRK1B Q9Y463 1/20 0.47
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
CYP2A6 P11509 1/20 0.46
FABP2 P12104 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5518679 0.96 SRD5A2 (0.61) SRD5A2MAPK1HPGDKMT2AMEN1
SCHEMBL9475353 0.89 SRD5A2 (0.59) SRD5A2MAPK1HPGDKMT2AMEN1
SCHEMBL9625609 0.88 HSD17B14 (0.62) SRD5A2MAPK1HPGDKMT2AMEN1
SCHEMBL11812457 0.86 HPGD (0.46) SRD5A2MAPK1HPGDKMT2AMEN1
SCHEMBL1681512 0.82 SRD5A2 (0.80) SRD5A2MAPK1HPGDCNR2CNR1
SCHEMBL9065412 0.82 SRD5A2 (0.80) SRD5A2MAPK1HPGDCNR2CNR1
SCHEMBL51827 0.82 SRD5A2 (0.80) SRD5A2MAPK1HPGDCNR2CNR1
SCHEMBL10697158 0.82 SRD5A2 (0.80) SRD5A2MAPK1HPGDCNR2CNR1
SCHEMBL7608517 0.81 CYP2A6 (0.48) SRD5A2MAPK1KMT2AMEN1NPC1
SCHEMBL743388 0.81 TSHR (0.60) SRD5A2KMT2AMEN1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP disclosed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US disclosed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP disclosed