Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | CCND1 | P24385 | 1/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967738 | 1.00 | LCK (0.62) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL2512334 | 0.83 | LCK (0.86) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL13338339 | 0.83 | LCK (0.86) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL2512336 | 0.83 | LCK (0.86) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL4701094 | 0.82 | LCK (0.64) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL4701093 | 0.82 | LCK (0.64) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL30749650 | 0.82 | NQO2 (0.57) | LCKABL1BCRHSD17B10GUSB | |
| SCHEMBL10973260 | 0.81 | ALDH1A1 (0.64) | GUSBCHATPTGS2 | |
| SCHEMBL10973255 | 0.81 | ALDH1A1 (0.64) | GUSBCHATPTGS2 | |
| SCHEMBL8967718 | 0.80 | LCK (0.67) | LCKCCNB2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530030-A | CHLORINATED HYDROXYSTILBENES | KIORITZ CORPORATIN (JP) | 1996-06-25 | — | — | US | claimed |
| CN-1076948-C | Nematicides against pine wood nematodes | KIORITZ CORP (JP) | 2002-01-02 | — | — | CN | disclosed |
| US-5530030-A | CHLORINATED HYDROXYSTILBENES | KIORITZ CORPORATIN (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5530030-A | CHLORINATED HYDROXYSTILBENES | KIORITZ CORPORATIN (JP) | 1996-06-25 | — | — | US | disclosed |
| CN-1105973-A | Nematicides against pine wood nematodes | KIORITZ CORP (JP) | 1995-08-02 | — | — | CN | disclosed |