SCHEMBL8967964

SCHEMBL8967964

Nc1ccccc1-c1ccc(O)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.72
ALOX5 P09917 7/20 0.54
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 3/20 0.52
ADORA2A P29274 1/20 0.49
ADORA1 P30542 1/20 0.49
ALOX15 P16050 3/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 1/20 0.48
HSP90AA1 P07900 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3784701 0.88 ALDH1A1 (0.64) APPALOX5ALDH1A1HSD17B10ALOX15
SCHEMBL3786765 0.88 HSD17B10 (0.64) APPALOX5ALDH1A1HSD17B10ADORA2A
SCHEMBL18238557 0.82 ESR2 (0.58) APPALDH1A1HSD17B10ADORA2AADORA1
SCHEMBL28742545 0.80 APP (0.82) APPALOX5ALDH1A1HSD17B10ADORA2A
SCHEMBL28871380 0.78 HSD17B10 (0.70) APPALOX5ALDH1A1HSD17B10ADORA2A
SCHEMBL28343138 0.78 ALDH1A1 (0.69) APPALOX5ALDH1A1HSD17B10ALOX15
SCHEMBL6011360 0.78 APP (0.52) APPALOX5ALDH1A1HSD17B10ADORA2A
SCHEMBL17573817 0.77 ALDH1A1 (0.52) APPALOX5ALDH1A1HSD17B10ALOX15
SCHEMBL17263732 0.77 ALDH1A1 (0.67) APPALOX5ALDH1A1HSD17B10ALOX15
SCHEMBL6480845 0.77 ALDH1A1 (0.83) ALDH1A1HSD17B10ADORA2AALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106575080-A Energy-sensitive resin composition 东京应化工业株式会社 2017-04-19 CN disclosed
WO-2016115360-A1 C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME COFERON, INC. (US) 2016-07-21 WO disclosed
WO-2016115360-A1 C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME COFERON, INC. (US) 2016-07-21 WO disclosed
US-5536865-A Process for the preparation of 5,6-dihydroxyindole and intermediate compounds L'OREAL (FR) 1996-07-16 US disclosed
US-5508464-A NITRATING OF A 4,5-DIBENZYLOXYPHENYLACETONITRILE, FOLLOWED BY DEBENZYLATION, HYDROGENATION AND CYCLIZATION L'OREAL (FR) 1996-04-16 US disclosed
US-5498746-A Process for the preparation of 5,6-dihydroxyindole and intermediate compounds L'OREAL (FR) 1996-03-12 US disclosed
EP-0381183-B1 Silver halide color photographic material containing pyrazolo(1,5-b) (1,2,4)triazole magenta coupler FUJI PHOTO FILM CO LTD (JP) 1995-10-04 EP disclosed
US-5410067-A Catalytic hydrogenation; cyclization L'OREAL (FR) 1995-04-25 US disclosed
EP-0254294-B1 METHOD OF PROCESSING A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL AND A COLOR DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1992-12-23 EP disclosed
US-5066575-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL CONTAINING PYRAZOLO (1,5-B)(1,2,4)TRIAZOLE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1991-11-19 US disclosed
US-5064751-A Stability, antifogging FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed