SCHEMBL4045452

SCHEMBL4045452

C=CCc1cc(O)cc(CC=C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.48
GABRB2 P47870 4/20 0.48
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 2/20 0.41
AKR1B1 P15121 2/20 0.41
GAA P10253 3/20 0.40
XDH P47989 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 3/20 0.39
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ALDH2 P05091 1/20 0.39
HPGD P15428 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4149652 0.85 GABRA1 (0.59) GABRA1GABRB2KDM4EPOLBAKR1B1
SCHEMBL5931901 0.85 GABRA1 (0.48) GABRA1GABRB2ESR1ESR2KDM4E
SCHEMBL14283804 0.85 ALOX5 (0.49) GABRA1GABRB2ESR1ESR2KDM4E
SCHEMBL14318839 0.83 ALOX5 (0.49) GABRA1GABRB2KDM4EGAAMEN1
SCHEMBL4306808 0.83 GABRA1 (0.47) GABRA1GABRB2ESR1ESR2KDM4E
SCHEMBL7852200 0.83 GABRA1 (0.47) GABRA1GABRB2KDM4EPOLBAKR1B1
SCHEMBL1420217 0.83 GABRA1 (0.47) GABRA1GABRB2KDM4EPOLBAKR1B1
SCHEMBL8517508 0.83 GABRA1 (0.47) GABRA1GABRB2KDM4EPOLBAKR1B1
SCHEMBL11261841 0.83 GABRA1 (0.47) GABRA1GABRB2ESR1ESR2KDM4E
SCHEMBL2461750 0.83 XDH (0.48) GABRA1GABRB2KDM4EPOLBAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290265-A Monomer compound and preparation method thereof, polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
JP-62138530-A None JP disclosed
CN-118290265-A Monomer compound and preparation method thereof, polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN disclosed
EP-2038332-B1 POLYVINYLIDENE FLUORIDE FILMS AND LAMINATES THEREOF AVERY DENNISON CORP (US) 2013-11-06 EP disclosed
US-20090202792-A1 POLYVINYLIDENE FLUORIDE FILMS AND LAMINATES THEREOF AVERY DENNISON CORPORATION (US) 2009-08-13 US disclosed
EP-2038332-A1 POLYVINYLIDENE FLUORIDE FILMS AND LAMINATES THEREOF Avery Dennison Corporation (US) 2009-03-25 EP disclosed
WO-2008002747-A1 POLYVINYLIDENE FLUORIDE FILMS AND LAMINATES THEREOF AVERY DENNISON CORPORATION (US) 2008-01-03 WO disclosed
US-6936655-B2 Crosslinkable flame retardant wire and cable compositions having improved abrasion resistance EQUISTAR CHEMICALS, LP (US) 2005-08-30 US disclosed
US-20050049343-A1 Crosslinkable flame retardant wire and cable compositions having improved abrasion resistance EQUISTAR CHEMICALS, LP 2005-03-03 US disclosed
EP-0891974-B1 Process for producing chromans KURARAY CO (JP) 2002-04-17 EP disclosed
US-5304668-A Bis-[4-(2,6-di-alkyl)phenolisilane derivatives as antiatherosclerotic agents MERRELL DOW PHARMACEUTICALS (US) 1994-04-19 US disclosed
US-5281738-A Anticholesterol agents MERRELL DOW PHARMACEUTICALS INC. (US) 1994-01-25 US disclosed
US-5155250-A 2,6-DI-ALKYL-4-SILYL-PHENOLS AS ANTIATHEROSCEROTIC AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1992-10-13 US disclosed
EP-0464844-A1 Novel bis (4-(2,6-di-alkyl)phenol)silane derivatives as antiatherosclerotic agents and as antioxidants MERRELL DOW PHARMACEUTICALS INC. (US) 1992-01-08 EP disclosed
EP-0464852-A1 Novel 2,6-di-alkyl-4-silyl-phenols as antiatherosclerotic agents and as antioxidants MERRELL PHARMACEUTICALS INC. (US) 1992-01-08 EP disclosed
EP-0376466-A2 Solvent-free solid polymer electrolyte and process for its preparation ASSOCIATED UNIVERSITIES, INC. (US) 1990-07-04 EP disclosed
US-4882243-A SOLVENT-FREE, BATTERIES POLYTECHNIC UNIVERSITY (US) 1989-11-21 US disclosed
JP-S62138530-A ORGANOPHOSPHAZENE POLYMER MARUZEN PETROCHEM CO LTD 1987-06-22 JP disclosed
US-4178180-A Copper physical development using heterocyclic ligand copper (I) complexes EASTMAN KODAK COMPANY (US) 1979-12-11 US disclosed
US-4156610-A Copper physical development using heterocyclic ligand copper(I) complexes EASTMAN KODAK COMPANY (US) 1979-05-29 US disclosed