Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 5/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338287 | 1.00 | ABCC9 (0.43) | ABCC9ABCB1SIRT2KDM4E | |
| SCHEMBL9524801 | 0.87 | ABCC9 (0.45) | ABCC9ABCB1SIRT2 | |
| SCHEMBL9525644 | 0.85 | ABCC9 (0.40) | ABCC9ABCB1SIRT2KDM4E | |
| SCHEMBL9525853 | 0.84 | ABCC9 (0.43) | ABCC9 | |
| SCHEMBL9525659 | 0.84 | ABCC9 (0.44) | ABCC9ABCB1 | |
| SCHEMBL9524618 | 0.83 | ABCB1 (0.41) | ABCC9ABCB1SIRT2KDM4E | |
| SCHEMBL9524374 | 0.82 | HTR2B (0.35) | — | |
| SCHEMBL9525760 | 0.82 | TRPM5 (0.42) | SIRT2 | |
| SCHEMBL9525156 | 0.82 | ABCB1 (0.38) | ABCC9ABCB1SIRT2KDM4E | |
| SCHEMBL9524383 | 0.82 | ABCC9 (0.43) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699429-A2 | Method of promoting hair growth | F. HOFFMANN-LA ROCHE AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| US-5470861-A | Method of promoting hair growth | HOFFMANN-LA ROCHE INC. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0298452-B1 | 2H-1-BENZOPYRANE DERIVATIVES SUBSTITUTED IN POSITION 4 BY ARYL OR N-HETEROARYL | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-30 | — | — | EP | disclosed |
| US-5118694-A | Hypotensive agents; treatment for cardiovascular and muscular disorders | HOFFMANN-LA ROCHE INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4971982-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, SMOOTH MUSCLE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0298452-A2 | 2H-1-benzopyrane derivatives substituted in position 4 by aryl or N-heteroaryl | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-11 | — | — | EP | disclosed |