Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | WNT3A | P56704 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968389 | 0.89 | NPC1 (0.49) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL29861033 | 0.84 | NPC1 (0.63) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL3282912 | 0.84 | NPC1 (0.63) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL19419913 | 0.81 | TP53 (0.56) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL8967782 | 0.80 | ERCC5 (0.46) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL6281987 | 0.79 | POLB (0.63) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| Bromide SCHEMBL8370980 | 0.78 | POLB (0.62) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL332837 | 0.74 | TTR (0.66) | NPC1SMN1; SMN2CTSDCTNNB1WNT3A | |
| SCHEMBL21023381 | 0.74 | MAPK1 (0.56) | NPC1SMN1; SMN2RAB9ATP53USP2 | |
| SCHEMBL9141895 | 0.74 | NPC1 (0.62) | NPC1SMN1; SMN2RAB9ATP53CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541032-A | CHARGE STABILIZERS WHICH ARE INSENSITIVE TO MOISTURE, HEAT RESISTANT AND PRODUCE CRISP, UNIFORM VISIBLE IMAGES OF HIGH COLOR INTENSITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |