Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 5/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969789 | 0.85 | ACHE (0.46) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968497 | 0.81 | ACHE (0.47) | ACHELMNACYP3A4PDE3BPDE3A | |
| SCHEMBL8969927 | 0.76 | ACHE (0.54) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968969 | 0.75 | ACHE (0.49) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969749 | 0.69 | ACHE (0.60) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL3387188 | 0.63 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL29416837 | 0.63 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL9381911 | 0.63 | ACHE (0.51) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968349 | 0.62 | ACHE (0.53) | ACHEBCHEMEN1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30600296 | 0.62 | MEN1 (1.00) | ACHEBCHEMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |