Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968412 | 0.85 | ACHE (0.46) | ACHECTSDPDE3BPDE3ACCR3 | |
| SCHEMBL8968349 | 0.80 | ACHE (0.53) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8968497 | 0.77 | ACHE (0.47) | ACHECTSDPDE3BPDE3ALMNA | |
| SCHEMBL8969701 | 0.74 | ACHE (0.58) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8969674 | 0.68 | ACHE (0.50) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8970485 | 0.67 | ACHE (0.49) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8969387 | 0.67 | ACHE (0.62) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8969190 | 0.66 | ACHE (0.89) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8968773 | 0.65 | ACHE (0.97) | ACHECTSDDRD2DRD4DRD3 | |
| SCHEMBL8968453 | 0.64 | ACHE (1.00) | ACHEDRD2DRD4DRD3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |