Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 4/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968570 | 0.84 | HTR2C (0.36) | HTR2CHTR2BHTR2ACHRNB2CHRNA4 | |
| SCHEMBL8969334 | 0.81 | — | — | |
| SCHEMBL8969095 | 0.81 | HTR2C (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969189 | 0.81 | ACHE (0.39) | HTR2CHTR2BHTR2ACTSD | |
| SCHEMBL8969710 | 0.80 | HTR2C (0.38) | HTR2CHTR2BHTR2ACHRNB2CHRNA4 | |
| SCHEMBL9540235 | 0.74 | CTSD (0.47) | CTSD | |
| SCHEMBL8969472 | 0.73 | HTR2A (0.32) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969727 | 0.73 | CTSD (0.32) | HTR2CHTR2BHTR2ACTSD | |
| SCHEMBL8969065 | 0.72 | CTSD (0.51) | HTR2CHTR2BHTR2ACHRNB2CHRNA4 | |
| SCHEMBL8969521 | 0.72 | CTSD (0.40) | HTR2CHTR2BHTR2ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |