Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969334 | 0.84 | — | — | |
| SCHEMBL8969189 | 0.84 | ACHE (0.39) | HTR2CHTR2BHTR2A | |
| SCHEMBL8968449 | 0.81 | HTR2C (0.38) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969774 | 0.78 | HTR2C (0.36) | HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL9540235 | 0.77 | CTSD (0.47) | KMT2AMEN1 | |
| SCHEMBL8969727 | 0.76 | CTSD (0.32) | HTR2CHTR2BHTR2A | |
| SCHEMBL8968791 | 0.73 | HTR2A (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969577 | 0.73 | CTSD (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969208 | 0.71 | KLK7 (0.32) | HTR2CHTR2A | |
| SCHEMBL8968334 | 0.69 | HTR2A (0.31) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |