Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431691 | 0.91 | LDHA (0.50) | LDHASLC6A4ALDH1A1TDP1KDM4E | |
| SCHEMBL542873 | 0.86 | KDM4E (0.50) | SLC6A4ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL1920821 | 0.82 | LDHA (0.47) | LDHASLC6A4ALDH1A1TDP1KDM4E | |
| SCHEMBL12960634 | 0.82 | KMT2A (0.52) | ALDH1A1KDM4ELMNAPKMGAA | |
| Methylamine SCHEMBL10763289 | 0.81 | KDM4E (0.47) | SLC6A4ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL10749798 | 0.80 | CA4 (0.64) | ALDH1A1KDM4ETSHRCRHBPCRHR2 | |
| SCHEMBL3395724 | 0.80 | MEN1 (0.46) | SLC6A4ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL9770385 | 0.79 | KDM4E (0.46) | SLC6A4ALDH1A1KDM4ELMNAPKM | |
| Dimethylamine SCHEMBL9504815 | 0.79 | KDM4E (0.46) | SLC6A4ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL17319347 | 0.79 | ALOX5 (0.46) | LDHASLC6A4TDP1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |