Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968557 | 0.96 | POLB (0.56) | POLBACHEBCHEKDM4EUSP2 | |
| SCHEMBL8968447 | 0.94 | POLB (0.58) | POLBACHEBCHEKDM4EUSP2 | |
| SCHEMBL5507502 | 0.82 | ALDH1A1 (0.60) | POLBACHEBCHEKDM4EUSP2 | |
| SCHEMBL8968731 | 0.82 | ACHE (0.56) | POLBACHEBCHEKDM4EUSP2 | |
| SCHEMBL8970467 | 0.78 | ACHE (0.48) | POLBACHEBCHEKDM4EUSP2 | |
| SCHEMBL8969605 | 0.78 | ACHE (0.48) | POLBACHEBCHEKDM4EUSP2 | |
| SCHEMBL8969554 | 0.78 | ACHE (0.61) | POLBACHEALDH1A1MEN1KMT2A | |
| SCHEMBL8970644 | 0.78 | ACHE (0.54) | POLBACHEALDH1A1MEN1KMT2A | |
| SCHEMBL8968470 | 0.77 | ACHE (0.64) | POLBACHEUSP2ALDH1A1ALOX15 | |
| SCHEMBL8968279 | 0.77 | ACHE (0.50) | POLBACHEBCHEKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |