Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968487 | 1.00 | KDM4E (0.32) | KDM4EMAPK1MAT2AIDO1TDO2 | |
| SCHEMBL15840530 | 0.66 | KDM4E (0.38) | KDM4E | |
| SCHEMBL30639058 | 0.64 | APAF1 (0.53) | KDM4EIDO1TDO2IDO2 | |
| SCHEMBL8969834 | 0.62 | BCHE (0.32) | — | |
| SCHEMBL8969895 | 0.62 | ALDH1A1 (0.52) | KDM4E | |
| SCHEMBL8969115 | 0.61 | ATM (0.36) | MAPK1 | |
| SCHEMBL31382855 | 0.61 | APAF1 (0.49) | IDO1TDO2IDO2 | |
| SCHEMBL31382846 | 0.61 | CHEK1 (0.67) | KDM4EIDO1TDO2IDO2 | |
| SCHEMBL15836406 | 0.59 | SMN1; SMN2 (0.34) | MAT2A | |
| SCHEMBL19992072 | 0.58 | PARP1 (0.66) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |