Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968425 | 0.94 | MEN1 (0.55) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE | |
| SCHEMBL6922778 | 0.82 | MAPT (0.45) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE | |
| SCHEMBL8968731 | 0.82 | ACHE (0.56) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE | |
| SCHEMBL5507502 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE | |
| SCHEMBL8969554 | 0.78 | ACHE (0.61) | ALDH1A1ACHESMN1; SMN2HPGDRAB9A | |
| SCHEMBL8968573 | 0.77 | POLB (0.65) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE | |
| SCHEMBL8968470 | 0.77 | ACHE (0.64) | ALDH1A1ACHEUSP2ALOX15SMN1; SMN2 | |
| SCHEMBL12040552 | 0.77 | SPR (0.34) | CYP1A2RAB9ANPC1CYP3A4GAA | |
| SCHEMBL5511719 | 0.77 | NPC1 (0.65) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE | |
| SCHEMBL10027304 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10CYP1A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |