Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 7/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968632 | 1.00 | FDFT1 (0.54) | FDFT1MMP13FDPSMAOBACHE | |
| SCHEMBL6377379 | 0.75 | FDFT1 (0.59) | FDFT1MMP13MMP2 | |
| SCHEMBL8419731 | 0.74 | FDPS (0.44) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL8421721 | 0.72 | FDFT1 (0.74) | FDFT1MMP13MMP2 | |
| SCHEMBL9432346 | 0.72 | FDFT1 (0.73) | FDFT1MMP13MMP2 | |
| SCHEMBL8772583 | 0.71 | MMP13 (0.63) | FDFT1MMP13MMP2 | |
| SCHEMBL9432198 | 0.71 | FDFT1 (0.76) | FDFT1MMP13MMP2 | |
| SCHEMBL5335178 | 0.70 | FDPS (0.75) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL5335182 | 0.70 | FDPS (0.75) | FDPSMAOBACHEBCHETTR | |
| SCHEMBL8968958 | 0.70 | MMP13 (0.59) | FDFT1MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |