Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968707 | 0.80 | KDM4E (0.33) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18470640 | 0.79 | LMNA (0.37) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL19859166 | 0.77 | LMNA (0.42) | LMNA | |
| SCHEMBL18477835 | 0.76 | LMNA (0.34) | LMNA | |
| SCHEMBL2544650 | 0.76 | LMNA (0.36) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2222034 | 0.75 | LMNA (0.61) | LMNA | |
| SCHEMBL8755729 | 0.74 | ALDH1A1 (0.45) | LMNAALDH1A1 | |
| SCHEMBL10983592 | 0.74 | TSHR (0.43) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8756103 | 0.74 | TP53 (0.36) | LMNAALDH1A1 | |
| SCHEMBL9336770 | 0.73 | MEN1 (0.38) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |