Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544650 | 0.82 | LMNA (0.36) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL8968668 | 0.80 | LMNA (0.39) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27623098 | 0.78 | MEN1 (0.36) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL8969144 | 0.77 | KDM4E (0.36) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL3358604 | 0.76 | MEN1 (0.42) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL363341 | 0.74 | KDM4E (0.45) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28586799 | 0.72 | KDM4E (0.44) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL4735982 | 0.72 | KDM4E (0.44) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL1537774 | 0.70 | HSD17B10 (0.39) | MEN1KMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL21774682 | 0.70 | PPARA (0.32) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |