Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969712 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL8969457 | 0.75 | DRD1 (0.33) | — | |
| SCHEMBL8969461 | 0.75 | DRD1 (0.33) | CYP3A4ALDH1A1 | |
| SCHEMBL8969143 | 0.75 | — | — | |
| SCHEMBL8969612 | 0.74 | PDE3B (0.34) | KDM4EALDH1A1GAA | |
| SCHEMBL8969417 | 0.73 | MAOA (0.36) | MAOAKDM4E | |
| SCHEMBL8969085 | 0.72 | NPC1 (0.34) | CYP3A4MAOBCTSDKDM4EALDH1A1 | |
| SCHEMBL8969494 | 0.71 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL8968478 | 0.71 | ACHE (0.43) | CTSDKDM4EALDH1A1 | |
| SCHEMBL8969486 | 0.71 | MAPK1 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |