Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969002 | 0.80 | ACHE (0.39) | ACHEKDM4ELMNA | |
| SCHEMBL8970442 | 0.78 | KDM4E (0.30) | MAOAACHEKDM4ELMNA | |
| SCHEMBL8969273 | 0.78 | ACHE (0.38) | MAOAACHE | |
| SCHEMBL8969712 | 0.76 | KDM4E (0.32) | KDM4E | |
| SCHEMBL8969143 | 0.74 | — | — | |
| SCHEMBL8968706 | 0.73 | MAPT (0.36) | MAOAKDM4E | |
| SCHEMBL8968558 | 0.72 | ACHE (0.48) | MAOAACHELMNA | |
| SCHEMBL8969163 | 0.72 | ACHE (0.50) | MAOAACHELMNA | |
| SCHEMBL8968441 | 0.71 | MAOA (0.34) | MAOAACHE | |
| SCHEMBL8968687 | 0.70 | MAOA (0.34) | MAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |