Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749360 | 0.87 | VCAM1 (0.55) | VCAM1ALDH1A1MAPK1MAPTGRIA1 | |
| SCHEMBL31672177 | 0.83 | VCAM1 (0.58) | VCAM1ALDH1A1MAPK1MAPTGRIA1 | |
| SCHEMBL709465 | 0.83 | MAPK1 (0.46) | VCAM1ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL9359167 | 0.83 | VCAM1 (0.63) | VCAM1ALDH1A1HTTMAPK1MAPT | |
| SCHEMBL463657 | 0.83 | VCAM1 (0.58) | VCAM1ALDH1A1MAPK1MAPTGRIA1 | |
| SCHEMBL31672176 | 0.83 | VCAM1 (0.58) | VCAM1ALDH1A1MAPK1MAPTGRIA1 | |
| SCHEMBL709464 | 0.78 | ALDH1A1 (0.42) | VCAM1ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL6222813 | 0.78 | TSHR (0.55) | ALDH1A1HTTNPC1MAPK1RAB9A | |
| SCHEMBL4048971 | 0.78 | GPR35 (0.56) | VCAM1ALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL404758 | 0.77 | VCAM1 (0.64) | VCAM1ALDH1A1MAPTGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932284-B2 | Indole sulfonamide modulators of progesterone receptors | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |