Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810366 | 0.86 | MERTK (0.60) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL2826350 | 0.83 | MERTK (0.60) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL694473 | 0.83 | HTT (0.54) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL2030257 | 0.83 | MERTK (0.53) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL18973568 | 0.82 | VCAM1 (0.47) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL27729647 | 0.82 | MERTK (0.67) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL1340217 | 0.82 | MERTK (0.62) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL1341420 | 0.82 | L3MBTL1 (0.64) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL890756 | 0.81 | KMT2A (0.50) | MERTKMEN1KMT2ALRRK2VCAM1 | |
| SCHEMBL9507369 | 0.81 | MAPT (0.68) | MERTKMEN1KMT2ALRRK2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388379-A | Organic total synthesis method of nimesulide derivative | 大连理工大学 | 2024-07-26 | — | — | CN | disclosed |
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |