Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.68 |
| ▸ | MERTK | Q12866 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729647 | 0.87 | MERTK (0.67) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL11322040 | 0.86 | MEN1 (0.82) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL11420199 | 0.84 | MERTK (0.53) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL2969404 | 0.84 | MERTK (0.71) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL27720337 | 0.83 | MAPT (0.77) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL28589234 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL810366 | 0.82 | MERTK (0.60) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL3128583 | 0.81 | HSPB1 (0.59) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL27713527 | 0.81 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL8968903 | 0.81 | MERTK (0.59) | MAPTMEN1KMT2AALDH1A1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5148215-A | — | — | None | — | — | JP | disclosed |
| JP-H05148215-A | AROMATIC DIAMINE CONTAINING CYANO GROUP AND ITS PRODUCTION | KANEGAFUCHI CHEM IND CO LTD | 1993-06-15 | — | — | JP | disclosed |