Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31563002 | 0.94 | SMN1; SMN2 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL17221115 | 0.94 | SMN1; SMN2 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL15865564 | 0.85 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL12059374 | 0.84 | MEN1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL2053429 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL8969198 | 0.83 | ACHE (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL2050608 | 0.83 | MEN1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL8969117 | 0.83 | ACHE (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL8968695 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL12457528 | 0.83 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |