Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511719 | 0.94 | NPC1 (0.65) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL8968275 | 0.89 | ALDH1A1 (0.71) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL8968942 | 0.83 | ALDH1A1 (0.80) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL2053429 | 0.83 | ALDH1A1 (0.71) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL2050608 | 0.83 | MEN1 (0.66) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL8968366 | 0.83 | ACHE (1.00) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL8968493 | 0.83 | ACHE (0.71) | ACHEPOLBMEN1KMT2AHDAC6 | |
| SCHEMBL5519389 | 0.83 | ALDH1A1 (0.70) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL5506562 | 0.82 | RAB9A (0.65) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL6920428 | 0.82 | MEN1 (0.63) | ACHEPOLBMEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272986-A | A compound for inhibiting acetylcholinesterase activity, and preparation method and uses thereof | XIAMEN MEDICAL COLLEGE | 2016-01-27 | — | — | CN | disclosed |
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0619819-A1 | 1-ARYLHETEROARYLALKYL SUBSTITUTED-1H-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |