Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934931 | 0.84 | ALDH1A1 (0.58) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL28324054 | 0.83 | TSHR (0.49) | TSHRALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL1128796 | 0.83 | CES2 (0.59) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL18734638 | 0.83 | RAB9A (0.50) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL11878300 | 0.83 | ALDH1A1 (0.45) | TSHRALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL7702480 | 0.81 | CES2 (0.50) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL28941987 | 0.80 | ALDH1A1 (0.55) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL14034553 | 0.80 | ALDH1A1 (0.48) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL422787 | 0.79 | RAB9A (0.62) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL9661207 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397658-B | Benzyl (meth) acrylate monomers suitable for microstructured optical films | 3M创新有限公司 | 2019-12-10 | — | — | CN | disclosed |
| CN-101054373-A | Method of synthesizing (E)-4-[2-Butyl-5-(2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-benzoic acid and salt thereof | SHANGHAI KESHENG PHARMACEUTICA (CN) | 2007-10-17 | — | — | CN | disclosed |
| EP-0696306-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025535-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
| US-5324788-A | A copolymer of a 4-acyloxystyrene and an acrylate modified by an alcohol to effect an ester interchange, an aminoplast crosslinking agent and solvent; enamel coatings; acid and solvent resistance; hardness; gloss; autos | EASTMAN KODAK COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0372470-A2 | Novel alpha-cyano-beta-oxopropionamides | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |