Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941667 | 0.83 | CHRM2 (0.50) | CHRM2CHRM4CHRM3CHRM1ALDH1A1 | |
| SCHEMBL28258749 | 0.78 | METAP2 (0.37) | CHRM2CHRM4CHRM3CHRM1SERPINE1 | |
| SCHEMBL28571588 | 0.78 | METAP2 (0.37) | CHRM2CHRM4CHRM3CHRM1SERPINE1 | |
| SCHEMBL11784008 | 0.78 | LMNA (0.31) | LMNASERPINE1 | |
| SCHEMBL17563236 | 0.77 | KDM4E (0.39) | CHRM2CHRM4CHRM3CHRM1KDM4E | |
| SCHEMBL17563238 | 0.77 | KDM4E (0.39) | CHRM2CHRM4CHRM3CHRM1KDM4E | |
| SCHEMBL17563239 | 0.77 | KDM4E (0.39) | CHRM2CHRM4CHRM3CHRM1KDM4E | |
| SCHEMBL17563237 | 0.77 | KDM4E (0.39) | CHRM2CHRM4CHRM3CHRM1KDM4E | |
| SCHEMBL17563459 | 0.77 | KDM4E (0.39) | CHRM2CHRM4CHRM3CHRM1KDM4E | |
| SCHEMBL19962806 | 0.76 | CHRM2 (0.46) | CHRM2CHRM4CHRM3CHRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |