Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.36 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.36 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969570 | 0.90 | SLC6A2 (0.39) | RARBPPARGPPARALYPLA1LYPLA2 | |
| SCHEMBL13000816 | 0.88 | FFAR4 (0.35) | RARBABCB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8933024 | 0.85 | FPR2 (0.36) | RARBCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8933186 | 0.84 | FPR2 (0.35) | RARBCYP3A4CYP2C8CYP2C9S1PR3 | |
| SCHEMBL17791142 | 0.84 | RARB (0.53) | RARBPPARGPPARARARARARG | |
| SCHEMBL9187787 | 0.83 | RARB (0.55) | RARBCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9187799 | 0.83 | RARB (0.55) | RARBCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL17791149 | 0.83 | RARB (0.55) | RARBPPARGPPARARARARARG | |
| SCHEMBL12739990 | 0.83 | LYPLA1 (0.36) | RARBLYPLA1LYPLA2ABHD16AFFAR4 | |
| SCHEMBL8958994 | 0.83 | FPR2 (0.34) | RARBCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |