SCHEMBL8933186

SCHEMBL8933186

CCCCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2)CC1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.35
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 1/20 0.34
RARB P10826 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
FASN P49327 1/20 0.34
MGLL Q99685 3/20 0.33
DPP4 P27487 1/20 0.32
CYP2C8 P10632 1/20 0.32
S1PR3 Q99500 1/20 0.32
APP P05067 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8933024 0.99 FPR2 (0.36) FPR2CNR1CNR2CYP3A4CYP2C9
SCHEMBL8959001 0.97 FPR2 (0.34) FPR2CNR1CNR2CYP3A4CYP2C9
SCHEMBL8958994 0.96 FPR2 (0.34) FPR2CNR1CNR2CYP3A4CYP2C9
SCHEMBL19985337 0.93 MAPT (0.36) FPR2CNR1CNR2CYP2C9GAA
SCHEMBL19985344 0.93 MAPT (0.36) FPR2CNR1CNR2CYP2C9GAA
SCHEMBL19985352 0.93 MAPT (0.36) FPR2CNR1CNR2CYP2C9GAA
SCHEMBL8932587 0.92 KDM1A (0.37) FPR2CYP3A4CYP2C9RARBGAA
SCHEMBL8932837 0.92 CYP2C9 (0.38) FPR2CYP3A4CYP2C9MAPTFASN
SCHEMBL17584846 0.92 CYP2C9 (0.36) FPR2CNR1CNR2CYP2C9GAA
SCHEMBL8933281 0.91 RARB (0.35) FPR2CYP3A4CYP2C9RARBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE KIF23, HCN3, FZD7 FPR2 1427/4885CNR1 2494/4885CNR2 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.