Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.32 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.32 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969305 | 0.91 | RARB (0.41) | RARBS1PR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8969570 | 0.88 | SLC6A2 (0.39) | RARBLYPLA1LYPLA2ABHD16ASLC6A2 | |
| SCHEMBL8969170 | 0.87 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B | |
| SCHEMBL8969153 | 0.87 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B | |
| SCHEMBL8969132 | 0.87 | NAAA (0.35) | SLC6A2SLC6A4SLC6A3S1PR1 | |
| SCHEMBL8970464 | 0.87 | FFAR4 (0.33) | RARBFFAR4S1PR3S1PR1GRIN1 | |
| SCHEMBL8969505 | 0.86 | RARB (0.37) | RARBFFAR4S1PR3LYPLA1LYPLA2 | |
| SCHEMBL12024278 | 0.86 | SLC6A2 (0.35) | FFAR4S1PR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8970844 | 0.86 | GRIN1 (0.32) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B | |
| SCHEMBL8970556 | 0.86 | GRIN1 (0.32) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |