Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970485 | 0.84 | ACHE (0.49) | ACHEBCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL9381911 | 0.81 | ACHE (0.51) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969199 | 0.74 | SPR (0.37) | ACHEMEN1LMNAKMT2AADRA1D | |
| SCHEMBL3387188 | 0.66 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL29416837 | 0.66 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30600296 | 0.65 | MEN1 (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968969 | 0.64 | ACHE (0.49) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL9540233 | 0.64 | ACHE (1.00) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL28663408 | 0.64 | MAPT (0.51) | ACHEBCHEMEN1ALDH1A1LMNA | |
| SCHEMBL8969927 | 0.62 | ACHE (0.54) | ACHEBCHEMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |