Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969226 | 0.87 | KDM4E (0.38) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969355 | 0.83 | HTR6 (0.41) | CYP11B1CYP11B2KDM4EALDH1A1GLA | |
| SCHEMBL8968968 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969480 | 0.81 | HTR6 (0.39) | CYP11B1CYP11B2KDM4EALDH1A1GLA | |
| SCHEMBL8968951 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8970270 | 0.75 | HTR6 (0.41) | CYP11B1CYP11B2KDM4EALDH1A1GLA | |
| SCHEMBL8968984 | 0.75 | PDE2A (0.36) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969401 | 0.73 | PDE2A (0.34) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8968872 | 0.72 | PTPN1 (0.34) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969345 | 0.72 | NR1H4 (0.39) | KDM4EALDH1A1POLBGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |