Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970270 | 0.87 | HTR6 (0.41) | NR1H4HTR6MAPTKDM4EALDH1A1 | |
| SCHEMBL8969480 | 0.83 | HTR6 (0.39) | NR1H4HTR6MAPTKDM4EALDH1A1 | |
| SCHEMBL8969355 | 0.81 | HTR6 (0.41) | HTR6MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8968968 | 0.78 | KDM4E (0.53) | HTR6MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8969226 | 0.75 | KDM4E (0.38) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8969177 | 0.73 | KDM4E (0.50) | HTR6MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8969761 | 0.73 | HTT (0.42) | MAPTSMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL8969266 | 0.72 | CYP11B1 (0.34) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8968363 | 0.72 | KDM4E (0.40) | HTR6MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL8968970 | 0.72 | KDM4E (0.48) | HTR6MAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |