Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969355 | 0.87 | HTR6 (0.41) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969266 | 0.87 | CYP11B1 (0.34) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8968968 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8970270 | 0.79 | HTR6 (0.41) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8968872 | 0.76 | PTPN1 (0.34) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969345 | 0.75 | NR1H4 (0.39) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL8969480 | 0.75 | HTR6 (0.39) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8969207 | 0.73 | GAA (0.41) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8968970 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL8968363 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1GLAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |