Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968351 | 0.89 | CTSD (0.46) | ACHECTSD | |
| SCHEMBL8969954 | 0.83 | EGFR (0.34) | — | |
| SCHEMBL8968403 | 0.83 | — | — | |
| SCHEMBL8969544 | 0.80 | CTSD (0.39) | CTSD | |
| SCHEMBL8969502 | 0.78 | KLK7 (0.32) | — | |
| SCHEMBL8969686 | 0.75 | PDE3B (0.45) | PDE3BPDE3ACTSD | |
| SCHEMBL8968867 | 0.75 | MAPK1 (0.32) | CTSD | |
| SCHEMBL8969474 | 0.75 | CTSD (0.30) | CTSD | |
| SCHEMBL8969224 | 0.75 | CTSD (0.30) | CTSD | |
| SCHEMBL8969678 | 0.74 | CTSD (0.39) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |