Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968644 | 0.78 | DRD1 (0.33) | CYP3A4 | |
| SCHEMBL8969224 | 0.77 | CTSD (0.30) | CTSD | |
| SCHEMBL8969474 | 0.74 | CTSD (0.30) | CTSD | |
| SCHEMBL8969954 | 0.74 | EGFR (0.34) | — | |
| SCHEMBL8969582 | 0.74 | — | — | |
| SCHEMBL8969633 | 0.73 | CTSD (0.41) | CTSDPDE4BCYP3A4MAPTMAOA | |
| SCHEMBL8969544 | 0.71 | CTSD (0.39) | CTSD | |
| SCHEMBL8968545 | 0.69 | ACHE (0.39) | — | |
| SCHEMBL8969030 | 0.66 | — | — | |
| SCHEMBL8970272 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |