Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 3/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969196 | 0.90 | CTSD (0.49) | CTSDHTR2AHTR2CHTR2BPNMT | |
| SCHEMBL8969954 | 0.83 | EGFR (0.34) | — | |
| SCHEMBL8969299 | 0.80 | PDE3B (0.40) | CTSD | |
| SCHEMBL8968867 | 0.75 | MAPK1 (0.32) | CTSD | |
| SCHEMBL8968874 | 0.74 | CTSD (0.41) | CTSDNOS3NOS1NOS2HTR2A | |
| SCHEMBL8968403 | 0.74 | — | — | |
| SCHEMBL8969521 | 0.73 | CTSD (0.40) | CTSDNOS3NOS1NOS2HTR2A | |
| SCHEMBL8969573 | 0.73 | HTR2C (0.32) | HTR2CHTR2B | |
| SCHEMBL8969474 | 0.72 | CTSD (0.30) | CTSD | |
| SCHEMBL8969224 | 0.72 | CTSD (0.30) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |