Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511124 | 0.82 | ACHE (0.69) | ACHEBCHEKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL8968931 | 0.82 | ACHE (0.47) | ACHEBCHECCR3KDM4EHSD17B10 | |
| SCHEMBL8970476 | 0.82 | ACHE (0.47) | ACHEBCHECCR3KDM4EHSD17B10 | |
| SCHEMBL5506588 | 0.74 | ACHE (0.62) | ACHEBCHEKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL8970050 | 0.70 | CCR3 (0.40) | ACHEBCHECCR3KDM4EHSD17B10 | |
| SCHEMBL3385589 | 0.67 | ACHE (0.67) | ACHEBCHEKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL5509472 | 0.66 | ACHE (0.43) | ACHEBCHEL3MBTL1ATMALDH1A1 | |
| SCHEMBL5505730 | 0.66 | ACHE (0.46) | ACHEBCHE | |
| SCHEMBL5513404 | 0.66 | ACHE (0.46) | ACHEBCHEKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9541773 | 0.66 | MEN1 (0.66) | ACHEBCHEKDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |